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Updated: Mar 12, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Prevention of preterm delivery: current challenges and future prospects
Maud D van Zijl1, Bouchra Koullali1, Ben Wj Mol2
1Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, the Netherlands.
Preventing preterm birth (<37 weeks gestation) is crucial for neonatal health. Risk stratification using maternal factors, history, and cervical length, followed by interventions like progesterone or cerclage, can reduce preterm birth rates.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Medicine
- Reproductive Health
Background:
- Preterm birth (PTB) is a leading cause of neonatal morbidity and mortality.
- Preventing PTB is a primary objective in obstetric care.
- Effective screening and prevention strategies are essential for improving neonatal outcomes.
Approach:
- Review of current literature on PTB risk factors and prevention.
- Analysis of screening tools, including cervical length measurements.
- Evaluation of preventive strategies for singleton and multiple gestations, considering risk levels.
Key Points:
- Risk stratification for PTB prevention should combine maternal risk factors, obstetric history, and screening tools.
- Cervical length measurement is a key screening tool for identifying at-risk pregnancies.
- Preventive strategies include progesterone, pessaries, and cerclage, with efficacy varying by population and risk profile.
Conclusions:
- Optimal PTB prevention requires tailored strategies based on individual risk assessment.
- Progesterone and cerclage are effective for preventing recurrent PTB.
- Further research, particularly on pessary use in high-risk women, is ongoing.
- Collaboration among healthcare providers, patient organizations, industry, and governments is vital to reduce PTB rates.
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