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Poor sleep quality in patients with multiple sclerosis: gender differences.

Marianna Vitkova¹, Jaroslav Rosenberger², Zuzana Gdovinova³

¹Department of Neurology Faculty of Medicine Safarik University Kosice Slovakia; Graduate School Kosice Institute for Society and Health Safarik University Kosice Slovakia.

Brain and Behavior

|November 16, 2016

Summary

Gender significantly impacts sleep quality in multiple sclerosis (MS) patients. Pain affects men, while depression and anxiety affect women with MS, necessitating gender-specific sleep disorder treatments.

Keywords:

gender differences multiple sclerosis sleep quality

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Area of Science:

Neurology
Sleep Medicine
Gender Studies

Background:

Sleep disturbances are common in multiple sclerosis (MS).
Factors influencing sleep quality may differ between genders in MS patients.
Understanding these differences is crucial for effective treatment.

Purpose of the Study:

To investigate gender-specific factors associated with poor sleep quality in individuals with MS.
To identify distinct predictors of sleep disturbances in men and women with MS.

Main Methods:

Data collected from 153 MS patients.
Utilized Pittsburgh Sleep Quality Index (PSQI), Hospital Anxiety and Depression Scale, and SF-36 pain item.
Statistical analysis included logistic regression and interaction models.

Main Results:

Pain was a significant predictor of poor sleep quality in men with MS (OR=12.7).
Depression (OR=4.1) and anxiety (OR=6.8) were significant predictors in women with MS.
A significant interaction between gender and pain was observed (OR=15.4).

Conclusions:

Sleep quality in MS patients is influenced by gender-specific factors.
Targeted interventions for pain in men and for depression/anxiety in women are needed.
Gender-tailored approaches are essential for managing sleep disorders in MS.