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Diffuse Alveolar Hemorrhage in Patients Undergoing Neurointervention: A Case Report
Yun Suk Choe1, Na Young Kim2, Ae Ryoung Lee1
1Department of Anesthesiology and Pain Medicine, Jeju National University Hospital, Jeju National University, Jeju Special Self-Governing Province, South Korea.
Anesthesiology and Pain Medicine
|November 16, 2016
Summary
Diffuse alveolar hemorrhage (DAH), a rare complication, can be life-threatening. This case highlights a potential link between clopidogrel use after neurointervention and DAH, emphasizing the need for physician awareness.
Area of Science:
- Neurology
- Pulmonology
- Pharmacology
Background:
- Diffuse alveolar hemorrhage (DAH) is a rare but severe complication.
- Clopidogrel is commonly used in neurointerventional surgery.
- No prior reports linked clopidogrel to DAH in neurointervention patients.
Observation:
- A 70-year-old male developed DAH post-cerebral angiography and coil embolization.
- Radiography revealed bilateral consolidation; bronchoscopy showed diffuse bronchial hemorrhage.
- Clopidogrel was discontinued, and mechanical ventilation was initiated.
Findings:
- A low dose of clopidogrel (75 mg) was associated with DAH.
- This case presents a novel complication of clopidogrel in neurointervention.
Implications:
- Physicians must consider DAH in neurointervention patients with respiratory distress and alveolar infiltrates.
- Awareness of this rare clopidogrel-induced DAH is crucial for prompt diagnosis and management.
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