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Melanoma-Associated Spongiform Scleropathy in Oculodermal Melanocytosis with Primary Orbital Melanoma
Roshni U Ranjit1, Ilya M Leyngold1, Curtis E Margo2
1Department of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa, Fla., USA.
Purpose:
To describe spongiform scleropathy in a patient with oculodermal melanosis and without evidence of uveal melanoma.
Methods:
Clinical-pathological correlation conducted in compliance with HIPPA (Health Insurance Privacy and Portability Act) regulations.
Results:
Melanoma-associated spongiform scleropathy was an incidental finding in an 87-year-old woman with oculodermal melanocytosis treated for primary orbital melanoma. All previously reported cases of this scleropathy have been associated with uveal melanoma.
Conclusions:
The mechanism of scleral degeneration in melanoma-associated spongiform scleropathy is unknown, and its clinical and prognostic significance is speculative. This is the first case of a so-called melanoma-associated spongiform scleropathy reported in an eye without uveal melanoma.
