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Related Experiment Video

Updated: Mar 12, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
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[Secondary diseases in high myopia].

F Ziemssen1, W Lagrèze2, B Voykov3

  • 1Department für Augenheilkunde, Universität Tübingen, Elfriede-Aulhorn-Str. 7, 72076, Tübingen, Deutschland. Focke.Ziemssen@med.uni-tuebingen.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|November 16, 2016
PubMed
Summary

High myopia significantly increases risks for secondary eye diseases like retinal detachment and glaucoma. Early detection and understanding of these risks are crucial for managing vision impairment.

Keywords:
Choroidal neovascularizationGlaucomaOpen angle glaucomaRetinal DetachmentStaphyloma

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Area of Science:

  • Ophthalmology
  • Medical Research

Background:

  • High myopia (axial length ≥ 26.5 mm) involves significant morphological and structural changes.
  • These changes lead to a considerably increased risk of secondary eye diseases.

Purpose of the Study:

  • To determine the incidence and mortality associated with high myopia.
  • To discuss the effects, clinical signs, and treatment recommendations for high myopia.
  • To present counselling strategies for patients with high myopia.

Main Methods:

  • A systematic literature search was conducted.
  • Discussion of basic principles and epidemiological investigations.

Main Results:

  • High myopia findings are dynamic, including choroidal neovascularization (2.5-5% prevalence), staphyloma, foveoschisis, and peripheral retinal degeneration.
  • Increased risk of retinal detachment post-lens surgery (HR 6.1), especially in younger individuals.
  • Associated primary open-angle glaucoma (OR 2.46) often diagnosed late due to low intraocular pressure.

Conclusions:

  • Advanced imaging techniques (MRI, OCT, wide-field imaging) enhance understanding of atrophic areas and staphyloma.
  • Knowledge of the associated risk profile is clinically significant for managing high myopia.