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Does rapid enteral feeding increase intestinal morbidity in very low birth weight infants? A retrospective analysis

Franziska Belling-Dierks1, Kirsten Glaser1, Johannes Wirbelauer1

  • 1a University Children's Hospital, University of Würzburg , Würzburg , Germany.

The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
|November 16, 2016
PubMed

Insights

A rapid enteral feeding strategy is safe for very low birth weight (VLBW) infants. This approach significantly reduces hospital stay and parenteral nutrition duration without increasing intestinal morbidity.

Area of Science:

  • Neonatalogy
  • Pediatric Gastroenterology
  • Clinical Nutrition

Background:

  • Enteral feeding is crucial for infant growth and development.
  • Optimizing feeding strategies in very low birth weight (VLBW) infants is essential to minimize complications.

Purpose of the Study:

  • To evaluate the safety and impact of a standardized rapid enteral feeding strategy on intestinal morbidity in VLBW infants.
  • To compare outcomes between infants receiving slow versus rapid enteral feeding regimens.

Main Methods:

  • Retrospective cohort study of 301 inborn VLBW infants.
  • Comparison of intestinal morbidity (necrotizing enterocolitis, intestinal perforation) between slow (10 ml/kg/day increase) and rapid (20 ml/kg/day increase) feeding groups.
  • Statistical analyses including univariate and multivariable logistic and linear regression.

Main Results:

  • No significant difference in intestinal morbidity between slow and rapid feeding groups (p=0.25).
  • No significant difference in all-cause mortality or late-onset sepsis.
  • Significantly shorter length of hospital stay (HS) and duration of parenteral nutrition (PEN) in the rapid feeding group (HS: -8.35 days, PEN: -7.13 days).

Conclusions:

  • A rapid enteral feeding strategy is safe for VLBW infants.
  • Implementation of rapid enteral feeding can lead to reduced hospital stay and parenteral nutrition duration.
  • This strategy offers potential benefits for resource utilization and infant recovery.
Abstract

Keywords:
Hospital stayVLBW infantsintestinal morbidityparenteral nutritionrapid enteral feeding

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