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Related Experiment Video

Updated: Mar 12, 2026

The In ovo CAM-assay as a Xenograft Model for Sarcoma

The In ovo CAM-assay as a Xenograft Model for Sarcoma

Published on: July 17, 2013

Breast Angiosarcoma with Exophytic Growth.

Donya Farrokh¹, Elaheh Modoodi², Yalda Fallah Rastegar²

¹Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran, Department of Radiology, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Archives of Iranian Medicine

|November 16, 2016

Summary

Primary breast angiosarcoma, a rare cancer, presents nonspecific findings on mammography and ultrasound. This case highlights imaging features of an exophytic angiosarcoma, aiding diagnosis of this uncommon breast malignancy.

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Area of Science:

Oncology
Radiology
Pathology

Background:

Primary breast angiosarcoma is a rare malignant neoplasm.
Diagnostic imaging modalities like mammography and ultrasound often yield nonspecific findings for this condition.
Early and accurate diagnosis is crucial for effective patient management.

Observation:

A 42-year-old woman presented with a hard, exophytic mass on the left breast with overlying skin discoloration.
Mammography showed a high-density, well-defined mass without microcalcifications or spiculations.
Ultrasound revealed a hypoechoic mass with a well-defined margin and heterogeneous echogenicity.

Findings:

Histological examination confirmed primary breast angiosarcoma.
The tumor exhibited exophytic growth characteristics.
Imaging findings, while nonspecific, were consistent with the final pathological diagnosis.

Implications:

This case underscores the importance of integrating imaging findings with clinical presentation and biopsy results for diagnosing rare breast tumors.
Radiologists and clinicians should consider angiosarcoma in the differential diagnosis of breast masses with unusual imaging features.
Understanding the imaging characteristics of primary breast angiosarcoma can potentially lead to earlier detection and improved patient outcomes.