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Updated: Mar 12, 2026

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
Published on: November 3, 2023
[Efficacy and safety of bilateral RIRS for renal lithiasis.]
José Luis Bauzá1, Enrique Pieras1, Valentí Tubau1
1Servicio de Urología. Hospital Universitari Son Espases. Palma de Mallorca. España.
Objectives:
We present our experience in single-stage bilateral retrograde intrarenal surgery (RIRS), analyzing the stone free rate (SFR), surgical time, hospital stay, pre- and post procedure creatinine, stone composition and complications.
Methods:
Between April 2012 and February 2016, 24 RIRS were carried out in 12 patients with bilateral renal stones. Patients were 9 men and 3 women with a median age of 47.5 (range:55),IMC: 23.59 (range: 12.5).
Results:
Mean number of stones per renal unit was 2.7 (range: 12), mostly located in the renal pelvis (40%), with an average size of 16.08±8.06 mm and an average stone burden of 258.54±242.59 mm². The SFR at 3 months was 83.33%. Average operation time was 75 minutes and median hospital stay was 2 days. Three complications were recorded (25%), all of them minor (Clavien I-II). No major complications were recorded (Clavien III-V).
Conclusions:
Single-stage bilateral RIRS is a safe and effective tool for the treatment of patients with bilateral renal stones.
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