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Author Spotlight: Rehabilitation of Stroke Patients With a Digital Occupational Training System
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Early rehabilitation after stroke.

Julie Bernhardt1, Erin Godecke, Liam Johnson

  • 1aThe Florey Institute of Neuroscience and Mental Health, University of Melbourne bNHMRC Centre of Research Excellence in Stroke Rehabilitation and Recovery, Melbourne cSchool of Health Science, Latrobe University, Melbourne dSpeech Pathology, School of Medical and Health Sciences, Edith Cowan University, Perth, Western Australia eClinical Exercise Science Research Program, Institute of Sport, Exercise and Active Living, Victoria University, Melbourne, Australia fInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.

Current Opinion in Neurology
|November 16, 2016
PubMed
Summary
This summary is machine-generated.

Early rehabilitation after stroke, including mobilization and targeted therapies within the first week, shows promise for aiding recovery. Further research is needed to optimize these interventions during the critical post-stroke window.

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Area of Science:

  • Neuroscience
  • Rehabilitation Medicine
  • Clinical Trials

Background:

  • Guidelines recommend early rehabilitation post-stroke, but evidence guiding practice is limited.
  • Brain neurobiology supports the concept that timely, appropriately dosed training enhances recovery.
  • Optimal timing and methods for initiating rehabilitation within the critical post-stroke window require further investigation.

Purpose of the Study:

  • To review recent clinical trials of early interventions (within 7 days of stroke) for stroke recovery.
  • To highlight advancements in early mobilization, aphasia, dysphagia, and upper limb treatments.
  • To discuss future research directions in early stroke rehabilitation.

Main Methods:

  • Review of recent clinical trials focusing on interventions commenced within 7 days of stroke.
  • Analysis of evidence for early mobilization, aphasia, dysphagia, and upper limb therapies.
  • Discussion of emerging trends and challenges in early rehabilitation research.

Main Results:

  • While the AVERT trial suggests caution in the immediate (<24h) post-stroke period, early mobility and mobilization appear safe and well-tolerated within the first week.
  • Large clinical trials for early aphasia therapy are forthcoming.
  • Targeted upper limb treatments with improved patient selection criteria are emerging.

Conclusions:

  • Early rehabilitation trials are complex but crucial for maximizing recovery potential in the critical repair window.
  • Standardizing 'early' recruitment, participant stratification, and long-term follow-up are essential for future research.
  • Improving trial standards and implementing new recommendations will advance the field of early stroke rehabilitation.