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Updated: Mar 12, 2026

Intra-Peritoneal Transplantation for Generating Acute Myeloid Leukemia in Mice
Published on: January 6, 2023
One Step Forward in the Challenging Arena of MLL-AF4 Leukemia
1Oncology Research Institute and Department of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Abstract:
MLL-AF4 leukemia is the predominant infant acute leukemia and has a poor prognosis. No current experimental models accurately reflect the human disease. Lin et al., in this issue of Cancer Cell, describe their model that recapitulates multiple key aspects of this aggressive disease, facilitating future mechanistic and preclinical studies.
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