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Histiocytosis X characterized by marked elevation of serum alkaline phosphatase and rapid destructive changes in the
1Dept. of Medicine 4, Kommunehospital, Copenhagen K, Denmark.
The European Respiratory Journal
|February 1, 1989
Abstract:
A 23 yr old man was admitted suspected of having a liver disease because of marked elevation of the serum alkaline phosphatase. A biopsy of the liver was without cholestasis. A skin biopsy of a papule was compatible with eosinophilic granuloma. Over a few months the patient developed severe restrictive lung disease. The elevation of the serum alkaline phosphatase was probably due to diffuse bone affection.