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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Pigmentation01:19

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The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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What is Cancer?02:12

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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
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Mutations01:35

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
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Skin cancer.

Lisa Berry

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    |November 17, 2016
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    Summary
    This summary is machine-generated.

    Skin cancer includes fatal malignant melanoma and common non-melanoma types. In the UK, 2013 saw over 14,000 malignant melanoma cases and 72,000 non-melanoma diagnoses.

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    Area of Science:

    • Dermatology and Oncology

    Background:

    • Skin cancer is categorized into malignant melanoma and non-melanoma types.
    • Malignant melanoma is potentially fatal, while non-melanoma skin cancers (e.g., squamous cell carcinoma, basal cell carcinoma) are rarely lethal.

    Purpose of the Study:

    • To present essential epidemiological facts regarding skin cancer incidence and mortality in the UK.

    Main Methods:

    • Data compilation of new skin cancer cases and deaths.
    • Categorization of skin cancers into malignant melanoma and non-melanoma subtypes.

    Main Results:

    • In 2013, the UK recorded 14,509 new cases of malignant melanoma.
    • In 2014, 2,459 deaths were attributed to malignant melanoma in the UK.
    • Non-melanoma skin cancers were more prevalent, with 72,100 new cases diagnosed in the UK in 2013.

    Conclusions:

    • Malignant melanoma represents a significant cause of cancer mortality.
    • Non-melanoma skin cancers exhibit higher incidence rates compared to malignant melanoma.