Related Experiment Videos
Redistribution of crossed cerebellar diaschisis
S M Kim1, C H Park, C M Intenzo
1Department of Radiation Oncology and Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, PA 19107.
Insights
Crossed cerebellar diaschisis is a brain condition where blood flow decreases in the cerebellum opposite a cerebral injury. Early I-123 IMP scans show this, with delayed scans revealing redistribution.
Area of Science:
- Neurology
- Neuroimaging
- Cerebrovascular Diseases
Background:
- Crossed cerebellar diaschisis (CCD) is a neuroimaging finding characterized by reduced blood flow in the cerebellar hemisphere contralateral to a cerebral infarction or ischemia.
- This phenomenon highlights the interconnectedness of cerebral and cerebellar function.
Observation:
- The study reports a case of crossed cerebellar diaschisis visualized using iodine-123 N-isopropyl-p-iodoamphetamine (I-123 IMP) brain scans.
- Early scans depicted the diaschisis, while delayed scans at three hours showed redistribution of the radiotracer.
Findings:
- I-123 IMP SPECT imaging can effectively demonstrate crossed cerebellar diaschisis.
- The observed redistribution on delayed scans suggests the involvement of normal non-specific amine receptor sites in the affected cerebellum.
Implications:
- This case illustrates the utility of SPECT imaging in diagnosing crossed cerebellar diaschisis.
- Understanding tracer redistribution may offer insights into the pathophysiology and potential recovery mechanisms of this condition.
Abstract:
Crossed cerebellar diaschisis refers to a functional decrease in blood flow to the cerebellar hemisphere contralateral to the infarcted or ischemic cerebral hemisphere. This phenomenon can be depicted using PET as well as using SPECT. This condition, seen on early I-123 IMP brain scans, can show redistribution on the three hour delayed scan, presumably due to normal non-specific amine receptor sites of the affected cerebellum. One such case is reported.