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Related Concept Videos

Human Genetics01:28

Human Genetics

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Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
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In Vitro Fertilization01:24

In Vitro Fertilization

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In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
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Trihybrid Crosses02:27

Trihybrid Crosses

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Trihybrid Crosses
Some of Mendel’s crosses examined three pairs of contrasting characteristics. Such a cross is called a trihybrid cross. A trihybrid cross is a combination of three individual monohybrid crosses. For example, plant height (tall vs. short), seed shape (round vs. wrinkled), and seed color (yellow vs. green).
The F1 generation plants of a trihybrid cross are heterozygous for all three traits and produce eight gametes. Upon self-fertilization, these gametes have an equal...
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Nondisjunction01:29

Nondisjunction

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During meiosis, chromosomes occasionally separate improperly. This occurs due to failure of homologous chromosome separation during meiosis I or failed sister chromatid separation during meiosis II. In some species, notably plants, nondisjunction can result in an organism with an entire additional set of chromosomes, which is called polyploidy. In humans, nondisjunction can occur during male or female gametogenesis and the resulting gametes possess one too many or one too few chromosomes.
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Nondisjunction01:21

Nondisjunction

5.5K
Nondisjunction is the failure of homologous chromosomes or sister chromatids to separate correctly and move to the opposite poles of the cells. This produces daughter cells with abnormal chromosome numbers.  Nondisjunction is common during anaphase I or anaphase II of meiosis.  Mutations in synaptonemal complex proteins that attach homologous chromosomes increase the chances of nondisjunction in anaphase I of meiosis I. In contrast, mutations in topoisomerases and condensins that hold...
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Nondisjunction01:29

Nondisjunction

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Related Experiment Video

Updated: Mar 12, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

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The Brazilian Twin Registry.

Paulo H Ferreira1, Vinicius C Oliveira2, Daniela R Junqueira2

  • 1Faculty of Health Sciences,University of Sydney,Sydney,New South Wales,Australia.

Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies
|November 18, 2016
PubMed
Summary

The Brazilian Twin Registry (BTR) was established to study genetic and environmental factors in diseases and behaviors. This growing resource facilitates twin research in South America and globally.

Keywords:
Brazildisease preventionhealth promotiontwin registrytwin studies

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Area of Science:

  • Human Genetics
  • Epidemiology
  • Behavioral Science

Background:

  • The Brazilian Twin Registry (BTR) was founded in 2013 to advance twin research in South America.
  • It serves as a crucial resource for investigating genetic and environmental influences on common diseases, phenotypes, and human behaviors.

Purpose of the Study:

  • To establish a comprehensive twin registry accessible to Brazilian and international researchers.
  • To facilitate studies on the interplay of genetic and environmental factors in various health and behavioral traits.

Main Methods:

  • Collaborative effort between Brazilian and Australian institutions, including universities and research foundations.
  • Recruitment via a longitudinal low back pain study, media campaigns, and social networking.
  • Data collection includes demographics, zygosity, anthropometrics, and health history through standardized questionnaires.

Main Results:

  • Currently, 291 twins are registered in the BTR.
  • Detailed data has been collected from 151 twins.
  • The BTR is a member of the International Network of Twin Registries.

Conclusions:

  • The BTR is a developing, valuable resource for twin research in Brazil and internationally.
  • Future plans aim to expand the registry significantly and foster national and international collaborations.