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Published on: May 2, 2013
Disseminated Mycobacterium tuberculosis following renal transplant with alemtuzumab induction
Adam Baghban1, Marwan Mikheal Azar2, Raffaele Mario Bernardo1
1Department of Internal Medicine, Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut, USA.
Abstract:
Mycobacterium tuberculosis presents unique challenges in the peritransplant period. Here, we describe a case of disseminated tuberculosis following renal transplantation with alemtuzumab induction immunosuppression in a patient with remotely treated pulmonary tuberculosis and ongoing risk factors for re-infection. We also review the available literature regarding the prevalence of tuberculosis infection following solid organ transplant and management of high-risk patients, including the role for isoniazid preventative therapy.
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