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Temperature-induced cardiac remodelling in fish.
Adam N Keen1, Jordan M Klaiman2, Holly A Shiels1
1Division of Cardiovascular Science, School of Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, M13 9NT, UK.
The Journal of Experimental Biology
|November 18, 2016
Summary
Fish hearts remodel structurally when acclimating to cold temperatures. This cardiac remodeling helps maintain heart function despite temperature changes, crucial for survival in variable climates.
Area of Science:
- Cardiovascular Physiology
- Fish Biology
- Environmental Adaptation
Background:
- Thermal acclimation induces significant cardiac remodeling in fish.
- This includes alterations in electrical, energetic, and structural properties of the ventricle.
Purpose of the Study:
- To review temperature-induced structural remodeling in the fish ventricle.
- To examine how structural changes modify cardiac functional properties.
Main Methods:
- Review of existing literature on fish cardiac remodeling.
- Analysis of structural and functional changes across different levels of biological organization.
Main Results:
- Cardiac remodeling alters stiffness, Ca2+ sensitivity, and force generation rate.
- These changes compensate for reduced function at lower temperatures.
- Remodeling is prevalent in fish active during seasonal temperature drops.
Conclusions:
- Ventricular remodeling is a key adaptation for fish maintaining activity in cold environments.
- Fish heart plasticity offers insights into climate change adaptation.
- Comparisons with mammalian ventricle adaptations highlight unique fish strategies.
