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Open discectomy vs microdiscectomy for lumbar disc herniation - a protocol for a pragmatic comparative effectiveness
Andreas Sørlie1, Sasha Gulati2, Charalampis Giannadakis2
1The Norwegian National Registry for Spine Surgery (NORspine), University Hospital of North Norway (UNN), Tromsø, Norway; Department of Neurosurgery, University Hospital of North Norway (UNN), Tromsø, Norway.
F1000Research
|November 18, 2016
Summary
This study compares microdiscectomy (MD) and open discectomy (OD) for lumbar disc herniation. It uses data from the Norwegian Registry for Spine Surgery to assess patient outcomes.
Area of Science:
- Neurosurgery
- Orthopedics
- Spine Surgery
Background:
- Lumbar microdiscectomy (MD) and open discectomy (OD) are surgical options for lumbar disc herniation.
- Previous studies comparing MD and OD have yielded conflicting results regarding effectiveness.
Purpose of the Study:
- To compare the relative effectiveness of microdiscectomy (MD) versus open discectomy (OD) for treating lumbar disc herniation.
- To analyze outcomes within a large patient cohort from routine clinical practice.
Main Methods:
- Observational study utilizing prospective data from the Norwegian Registry for Spine Surgery (NORspine).
- Inclusion of patients undergoing either MD or OD for lumbar disc herniation.
- Primary outcome: change in Oswestry Disability Index (ODI) at 12 months.
- Secondary outcomes: leg pain improvement, Euro-Qol-5D (EQ-5D) quality of life changes, surgical complications, procedure duration, and hospital stay.
Main Results:
- Data collection from the NORspine registry is ongoing.
- Analysis will focus on comparing ODI, leg pain, and EQ-5D scores between MD and OD groups.
- Complications, surgical time, and hospital stay will also be compared.
Conclusions:
- This study aims to provide robust evidence on the comparative effectiveness of MD and OD for lumbar disc herniation.
- Findings will inform clinical decision-making and patient management strategies.
