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Related Experiment Videos

Pediatric herpes simplex masquerading as varicella-zoster.

A Aguirre Vila-Coro1, J F del Cotero, S Bonafonte

  • 1University of Texas Health Science Center, Houston, Texas 77030-1697.

Annals of Ophthalmology
|February 1, 1989
PubMed
Summary

A three-year-old girl experienced a generalized Herpes simplex virus infection and corneal ulcer. Prompt antiviral treatment led to healing, highlighting the importance of accurate diagnosis for Herpes simplex virus in children.

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Area of Science:

  • Virology
  • Ophthalmology
  • Pediatrics

Background:

  • Herpes simplex virus (HSV) infections can manifest in various ways, including cutaneous and ocular involvement.
  • Accurate differentiation between HSV, varicella, and Herpes zoster is crucial for appropriate management, especially in pediatric cases.

Observation:

  • A three-year-old girl presented with a generalized cutaneous rash and a dendritic corneal ulcer.
  • Initial diagnoses included varicella and Herpes zoster ophthalmicus, leading to the prescription of topical corticosteroids.

Findings:

  • Laboratory tests, including enzyme-linked immunosorbent assay (ELISA) and cultures, confirmed the presence of Herpes simplex virus (HSV).
  • The patient received topical antiviral therapy.

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Implications:

  • This case underscores the importance of considering HSV in the differential diagnosis of pediatric cutaneous and ocular lesions.
  • Timely and accurate diagnosis of HSV infection is critical to prevent potential complications and ensure effective treatment, avoiding therapies like corticosteroids that can exacerbate viral infections.