Prostate Artery Embolization for Complete Urinary Outflow Obstruction Due to Benign Prostatic Hypertrophy

Area of Science:

• Interventional Radiology
• Urology
• Vascular Medicine

Background:

• Acute urinary retention (AUR) due to benign prostatic hypertrophy (BPH) often necessitates catheterization.
• Failed trial without catheter (TWOC) presents a challenge in managing BPH-related AUR.
• Prostatic artery embolization (PAE) is explored as a minimally invasive treatment option.

Purpose of the Study:

• To evaluate the effectiveness of PAE in catheter weaning for BPH patients with AUR and failed TWOC.
• To assess PAE's efficacy in relieving obstructive urinary symptoms.
• To compare outcomes with a control group of BPH patients without AUR.

Main Methods:

• Prospective study including 18 patients with BPH-induced AUR and failed TWOC, and 19 controls.
• PAE performed using 100-300 μm microspheres.
• Outcome measures included catheter weaning, complications, symptom changes, urodynamics, and prostate volume reduction.

Main Results:

• Successful catheter weaning in 87.5% of patients within 14 days.
• No procedure-related complications reported.
• No significant differences in demographics or outcomes between the PAE group and controls.

Conclusions:

• PAE is likely safe and effective for catheter weaning and symptom relief in BPH patients with AUR.
• Treatment outcomes following PAE appear comparable to those in BPH patients without AUR.