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Updated: Mar 12, 2026

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
Published on: April 25, 2025
High Frequency of OXA-253-Producing Acinetobacter baumannii in Different Hospitals in Recife, Brazil
Felipe Lira de Sá Cavalcanti1,2, Carina Lucena Mendes-Marques2, Crhisllane Rafaele Dos Santos Vasconcelos2,3
1Laboratório de Resistência Microbiana, Instituto de Ciências Biológicas, Universidade de Pernambuco, Recife, Brazil.
Abstract:
Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with blaOXA-253 In all strains, the blaOXA-253 gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The reported data emphasize the successful transmission of the blaOXA-253 gene through a large area and the tendency for this resistance determinant to remain in the A. baumannii population.
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