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A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Parenchymal density changes in acute pulmonary embolism: Can quantitative CT be a diagnostic tool? A preliminary
Ikram Eda Duman1, Canan Cimsit1, Sehnaz Olgun Yildizeli2
1Marmara University Training and Research Hospital, Department of Radiology, Istanbul, Turkey.
Purpose:
Determine the ability of quantitative CT (QCT) in defining parenchymal density changes in acute pulmonary embolism (PE).
Material & Methods:
Mean lung density (MLD) and percentage distribution values (PDV) were calculated in 34 patients suspected of PE using software application based on computerized volumetric anatomical segmentation.
Results:
Total, left, and right MLD differed significantly between emboli positive(n=23) and negative(n=11) groups(p<0.006, p<0.009, p<0.014). PDVs differed between groups (p<0.05) except for LUZ and RLZ. When PE was present in lobe &/segment branches, PDVs were significantly lower except RUZ.
Conclusion:
QCT is a promising application for defining parenchymal density changes in PE revealing potential functional impact of emboli. This preliminary study suggests QCT could provide added value to CTPA in peripheral PE.
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