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Published on: June 11, 2012
Hypertension control and care at Mulago Hospital ambulatory clinic, Kampala-Uganda
Isaac Ssinabulya1, Yvonne Nabunnya2, Brian Kiggundu2
1Makerere University College of Health Sciences, Kampala, Uganda. ssinabulyaisaac@gmail.com.
Insights
Hypertension control is poor in African tertiary clinics, with suboptimal blood pressure management and inadequate investigation documentation. Common medications include Angiotensin receptor blockers/Angiotensin converting enzyme inhibitors, calcium channel blockers, and thiazide diuretics.
Area of Science:
- Cardiology
- Public Health
- Internal Medicine
Background:
- Hypertension is a global health issue, prevalent in developing nations and a primary cause of cardiovascular disease in Africa.
- Inadequate hypertension control in resource-limited settings leads to increased rates of stroke, heart failure, kidney failure, and premature death.
Purpose of the Study:
- To assess blood pressure control levels.
- To evaluate the documentation of basic investigations and hypertension treatment choices.
- To analyze patient data from a hypertension clinic at Mulago National Referral Hospital.
Main Methods:
- A retrospective chart review was conducted for patients attending the hypertension clinic between September 2012 and February 2013.
- Data collected included blood pressure control, documented investigations for hypertension complications, and prescribed anti-hypertensive medications.
Main Results:
- Only 26.7% of 741 reviewed patients achieved blood pressure control (BP < 140/90 mmHg).
- Documentation of biophysical measurements like waist circumference was very low (0.3%).
- While 64.2% had at least one investigation documented, only 13.9% had all recommended investigations (CBC, urinalysis, RFTs, CXR, Echo, ECG). Commonly documented were RFTs (45.5%), ECG (45.2%), and Echo (44.2%).
- Angiotensin receptor blockers (ARBs)/Angiotensin converting enzyme inhibitors (ACEI), calcium channel blockers, and thiazide diuretics were frequently prescribed, often in combination therapy (42.2% on three agents).
Conclusions:
- Blood pressure control is suboptimal in this tertiary clinic, with inadequate investigation documentation.
- Combination therapy with ARBs/ACEIs, calcium channel blockers, and thiazide diuretics is common.
- Further investigation into renal and cardiac complications and reasons for poor BP control is needed, alongside interventions to improve outcomes.
Background:
Hypertension is as prevalent in many developing countries, as in the developed world and is the leading cause of cardiovascular morbidity and mortality in Africa. The control of hypertension in this resource limited setting is inadequate, a situation that translates into poorer outcomes in form of increasing incidences of stroke, heart failure, kidney failure and therefore early cardiovascular death.
Methods:
This was a chart review of all the patients seen during the months of September 2012 to February 2013. We determined the level of blood pressure control, basic investigations documented as well as the choice of hypertensive treatment among patients attending a hypertension clinic in a national referral hospital, Mulago.
Results:
Of the 741 patients whose charts were reviewed the median age was 60 years, Inter quartile range (IQR) was 51-71. Six hundred forty-two (86.6%) were females. Blood pressure (BP) control defined as BP lowering to at least 140/90 was seen in only 198 (26.7%) patients. Biophysical measurement documentation was very low especially for waist and hip circumference at 0.3%. Majority of patients, 476 (64.2%) had at least one documented investigation for the complications of hypertension. Only 103 (13.9%) had all investigations documented in their charts. The investigations included; complete blood count (CBC), urinalysis, renal function tests (RFTs), Chest X-Ray (CXR), echocardiography (Echo) and electrocardiography (ECG). The commonly documented investigations were RFTs (45.5%), ECG (45.2%) and Echo (44.2%). The commonly prescribed anti hypertensive medications were; Angiotensin receptor blockers (ARBs)/Angiotensin converting enzyme inhibitors (ACEI) (72.74%), calcium channel blockers (72.3%) and thiazide diuretics (68.6%). Majority of patients were receiving three anti hypertensive medications 313 (42.2%), with 149 (43.6%) of these, on an ACEI/ARB, a calcium channel blocker and a thiazide diuretic.
Conclusion:
Blood pressure control is suboptimal in a tertiary clinic setting at Mulago hospital and documentation of investigations is inadequate. ARB/ACEI, Calcium channel blockers and thiazide diuretics were the commonly prescribed anti hypertensive medications. There is a great need to investigate for renal and cardiac complications as well as exploring reasons for inadequate blood pressure control and consider appropriate interventions to avert bad outcomes.
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