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[Parathyroid disease: The full spectrum, from adenoma to carcinoma. Report of 3 cases]
Enrique Stoopen-Margain1, Sofía Valanci-Aroesty2, Leopoldo Castañeda-Martínez2
1Cirugía endocrina, Centro Médico ABC, Ciudad de México, México.
Background:
Primary hyperparathyroidism is a disease characterised by the autonomous production of parathyroid hormone. The most common cause is an adenoma, followed by hyperplasia, and rarely carcinoma.
Clinical Cases:
Three cases are presented. The first case is associated with a brown tumour that was diagnosed as hyperplasia after study and surgery. The second case was related to pathological fractures, and a lower right adenoma 236 times bigger than a normal parathyroid was excised. The last case presented with abdominal pain and heartburn. Histopathology reported a carcinoma, which was removed using surgery en bloc. All patients have improved.
Conclusion:
Hyperparathyroidism symptoms are very difficult to identify and diagnose, thus a detailed and broad approach is needed when hyperparathyroidism is suspected.
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