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Updated: Mar 12, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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Difluorocyclobutylacetylenes as positive allosteric modulators of mGluR5 with reduced bioactivation potential

Andrew P Degnan1, Darrell Maxwell1, Anand Balakrishnan1

  • 1Bristol-Myers Squibb Co., Research and Development, 5 Research Parkway, Wallingford, CT 06492, United States.

Bioorganic & Medicinal Chemistry Letters
|November 19, 2016
PubMed

Keywords:
BioactivationCognitionPAMsSchizophreniamGluR5

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