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Normal testes asymmetry evaluated by apparent diffusion coefficient and magnetization transfer ratio.

Athina C Tsili1, Alexandra Ntorkou1, Dimitrios Giannakis2

  • 11 Department of Clinical Radiology, Medical School, University of Ioannina, Ioannina, Greece.

Acta Radiologica (Stockholm, Sweden : 1987)
|November 19, 2016
PubMed
Summary
This summary is machine-generated.

Normal testes exhibit size asymmetry, with the right typically larger. Magnetization transfer ratio (MTR) differences suggest structural and functional asymmetry, while apparent diffusion coefficient (ADC) shows no significant variation.

Keywords:
Magnetic resonance imaging (MRI)diffusion-weighted MRIleft–right asymmetrymagnetization transfer contrast imagingtestis

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Area of Science:

  • Radiology
  • Human Anatomy
  • Medical Imaging

Background:

  • Human testes naturally display asymmetry, with the right often larger and the left hanging lower.
  • Magnetic Resonance Imaging (MRI) is crucial for diagnosing testicular conditions.

Purpose of the Study:

  • To investigate the relationship between normal testicular asymmetry and imaging metrics.
  • To determine if apparent diffusion coefficient (ADC) and magnetization transfer ratio (MTR) correlate with natural testicular size differences.

Main Methods:

  • Included 106 healthy men's testes for analysis.
  • Calculated testicular volume (TV) using the ellipsoid formula.
  • Acquired diffusion-weighted imaging (DWI) and magnetization transfer imaging (MTI) using MRI.

Main Results:

  • Confirmed significant size asymmetry: right testis volume (16.77 ± 4.84 mL) was greater than the left (15.97 ± 4.45 mL).
  • No significant difference was found in apparent diffusion coefficient (ADC) between right and left testes.
  • Observed a statistically significant difference in magnetization transfer ratio (MTR) between the right (46.6 ± 2.1%) and left (46.0 ± 2.2%) testes.

Conclusions:

  • Testicular size asymmetry is confirmed in healthy males.
  • Magnetization transfer ratio (MTR) differences suggest underlying structural and functional asymmetry in normal testes.
  • Further research may elucidate the clinical implications of these asymmetries.