[Eosinophilic histiocytic granuloma of the vulva and cervix]

In a patient aged 29 a recurrent histiocytic granuloma developed in vulva, vagina and cervix. The patient was treated by cervical resection followed by irradiation. Langerhans cells with Birbeck granules in plasma of the cells, besides multiple eosinophilic leucocytes were evidenced by electron microscope. The eosinophilic histiocytic granuloma is suggested to be a benign variety of histiocytosis X, whose basic cellular component is the Langerhans cell. Eosinophil leucocytes represent a local immune response in the benign variety of histiocytosis X.