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Paramyxoviruses for Tumor-targeted Immunomodulation: Design and Evaluation Ex Vivo
Published on: January 7, 2019
Minimizing Hazards Associated With Live-Virus Immunotherapeutic Cancer Vaccines
1National Cancer Institute, National Institutes of Health.
Abstract:
Therapeutic cancer vaccines that use attenuated vaccinia viruses as delivery vectors are undergoing clinical trials at dozens of sites internationally. Even in an attenuated form, these live viruses can cause severe illness if they are accidentally transmitted to immunocompromised people, pregnant women, or people with certain skin conditions. Oncology nurses should become familiar with how to manage patients' vaccine injection sites to minimize these risks to patients' close contacts and the community at large. .
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