Patent ductus venosus presenting with cholestatic jaundice in an infant with successful trans-catheter closure using

Anith Chacko1, Celeste Kock2, Jayneel A Joshi3

  • 1Department of Radiology, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa.

Insights

Persistent ductus venosus is a rare cause of infant cholestatic jaundice. Transcatheter occlusion with a vascular plug successfully treated a 5-week-old infant with this condition.

Area of Science:

  • Pediatric Gastroenterology
  • Neonatal Medicine
  • Interventional Cardiology

Background:

  • Cholestatic jaundice in infants often presents diagnostic challenges.
  • Persistent ductus venosus is an uncommon etiology for neonatal cholestasis.
  • Management strategies for ductus venosus-induced cholestasis are not well-established.

Observation:

  • A 5-week-old female infant presented with persistent cholestatic jaundice.
  • The jaundice was attributed to a persistent ductus venosus.
  • The infant experienced complications necessitating intervention.

Findings:

  • Successful transcatheter occlusion of the persistent ductus venosus was performed.
  • A vascular plug device was utilized for the occlusion.
  • The infant's cholestatic jaundice resolved post-procedure.

Implications:

  • Transcatheter occlusion is a viable treatment option for persistent ductus venosus causing cholestatic jaundice.
  • This case highlights a minimally invasive approach for a rare neonatal condition.
  • Further research may explore the efficacy of vascular plug devices in similar pediatric cases.

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