HINT: a database of annotated protein-protein interactions and their homologs
Ashwini Patil1, Haruki Nakamura1
1Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Abstract:
Despite the abundance of protein-protein interaction databases currently available online, a source that identifies and lists similar interactions in different species is lacking. The Homologous Interactions (HINT) database is such a collection of protein-protein interactions and their homologs in one or more species. The interactions and their homologs are annotated with Eukaryotic Cluster of Orthologous Groups (KOG) IDs, InterPro domains, Gene Ontology (GO) terminology and Protein Data Bank (PDB) structures. HINT is available as an interactive Web server at http://helix.protein.osaka-u.ac.jp/hint/.
Related Concept Videos
Protein-protein Interfaces
Protein-Protein Interfaces
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Protein Networks
Protein Organization
The primary structure of a protein is its amino acid sequence....
Protein Complexes with Interchangeable Parts


