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Updated: Mar 11, 2026

High Throughput Single-cell and Multiple-cell Micro-encapsulation
Published on: June 15, 2012
A nano-sized container for specific encapsulation of isolated water molecules
Roy Lavendomme1, Lionel Marcélis2, Johan Wouters3
1Laboratoire de Chimie Organique, Université libre de Bruxelles (ULB), Avenue F.D. Roosevelt 50, CP160/06, B-1050 Brussels, Belgium. ijabin@ulb.ac.be and Laboratoire de Résonance Magnétique Nucléaire Haute Résolution, Université libre de Bruxelles (ULB), Avenue F.D. Roosevelt 50, CP160/08, B-1050 Brussels, Belgium.
Abstract:
A calix[4]arene-based molecular box was synthesized. Its properties were characterized through XRD and extensive NMR studies. This receptor is able to encapsulate specifically two isolated water molecules in both non-protic and protic solvents. This is a consequence of high size, geometric and electronic complementarity between the host and the water molecules.

