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Updated: Mar 11, 2026

Isolation, Processing and Analysis of Murine Gingival Cells
Published on: July 2, 2013
[Clinical study on the effect of anti-gingivitis IgY toothpaste in control of gingivitis and dental plaque]
Wei Zhang1, Xi-Ping Feng, Dan-Ying Tao
1Department of Preventive and Dentistry, Shanghai Ninth people's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; Shanghai Key Laboratory of Stomatology. Shanghai 200011, China.
Purpose:
To observe the effect of anti-gingivitis IgY toothpaste in control of gingivitis and plaque.
Methods:
The study was a double-blind, randomized, parallel-controlled clinical trail with a total of 100 subjects who were divided into two groups, experimental group and control group. The subjects in experimental group used anti-gingivitis IgY toothpaste to brush twice daily for 3 minutes, and the subjects in control group used none anti-gingivitis IgY toothpaste. The examiner recorded GI, PI and BOP index of all subjects at the baseline, 6-weeks and 12-weeks. SPSS21.0 software package was used for statistical analysis.
Results:
Twelve weeks later, there were significant differences in GI and BOP between the two groups. Yet no significant difference was found in PI.
Conclusions:
Anti-gingivitis IgY toothpaste is effective in control of gingivitis.

