[Resorption and postoperative anti-inflammatory effect of soluble indomethacin eyedrops]

Absorption of the 0.3% Indomethacin-soluble ophthalmic solution produced in the 2nd Department of Ophthalmology in Budapest is more rapid and reaches a higher concentration in the aqueous humour than 0.5% Indomelol or 1.0% Indoptol ophthalmic solution. This fact was demonstrated in human aqueous humour, too, taken from the eye 1 h after administration of the drops at the beginning of the cataract operation. The Indomethacin-soluble eye drops are especially effective in preventing a postoperative increase in the intraocular pressure as a result of inflammation. On the first postoperative day following the cataract operation a 26.2% increase in the intraocular pressure in was found in the patients. In eyes treated with Indomethacin this number was 14.0%. The difference is significant (p = 0.04).