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Ability of alpha (but not beta) form interleukin-1 to support DNA synthesis in human tonsillar B cells
G Gallagher1, J F Christie, W H Stimson
1Immunology Division, University of Strathclyde, Glasgow, Scotland.
International Archives of Allergy and Applied Immunology
|January 1, 1989
Abstract:
The ability of the two forms of recombinant human interleukin-1 (alpha and beta) to support DNA synthesis in human tonsillar B cells was assessed. The results suggested that in two out of three cases the alpha form was able to support DNA synthesis when the beta form was not. These results support the hypothesis that each form of human interleukin-1 has a different role in supporting the growth of human B cells.