Related Experiment Video
Updated: Mar 11, 2026

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
Published on: February 20, 2017
The not so innocent heart murmur: a 5-year experience
Shaw-Hua Kueh1, Thomas Pasley1, Miriam Wheeler1
1Department of Cardiology, Auckland Hospital, Auckland, New Zealand.
Insights
Auckland City Hospital’s Heart Murmur Clinic (HMC) identified significant structural heart disease in 156 adult patients. This highlights the clinic’s value in early detection and intervention for conditions like aortic stenosis and mitral regurgitation.
Area of Science:
- Cardiology
- Clinical Medicine
Background:
- Auckland City Hospital established a Heart Murmur Clinic (HMC) to assess asymptomatic systolic murmurs.
- The clinic aims for early intervention or reassurance for structural heart disease.
- The benefit of HMCs in adults was previously unclear.
Purpose of the Study:
- Review clinical demographics and echocardiographic data of HMC patients.
- Determine the prevalence of significant structural heart disease.
- Identify common structural abnormalities in adult patients with murmurs.
Main Methods:
- Retrospective review of 1221 adult patients (≥15 years) presenting with asymptomatic systolic murmurs.
- Data collected between March 2010 and December 2015.
- Excluded patients with prior cardiac surgery or known heart disease.
Main Results:
- Significant cardiac disease found in 156 patients (12.8%); 23 required surgery.
- Most common pathologies: aortic stenosis (43) and mitral regurgitation (48).
- Older patients (>65 years) showed a higher prevalence of structural heart disease (16% vs 11%).
Conclusions:
- The HMC effectively screens patients with low assessment priority.
- A significant proportion of patients had actionable structural heart disease.
- Early detection and intervention via HMC may improve patient outcomes.
Background:
Auckland City Hospital (ACH) established a Heart Murmur Clinic (HMC) with the aim of providing prompt assessment of patients with asymptomatic systolic murmurs. This may lead to early intervention and improved outcomes if significant structural heart disease is detected and reassurance if no significant findings are found. Similar clinics for children have proven beneficial; the benefit of a HMC in an adult population has been difficult to determine.
Aim:
To review the clinical demographics and echocardiographic information of patients presenting to our HMC, to assess what proportion of significance structural heart disease had and determine the common structural abnormalities in this population.
Methods:
This is a retrospective review of patients aged ≥15 years presenting to our HMC between March 2010 and December 2015 with an asymptomatic systolic murmur. Patients with previous cardiac surgery or known congenital or valvular heart disease were excluded.
Results:
A total of 1221 patients was reviewed over the 5-year period; 980 underwent echocardiography. Significant cardiac disease was detected in 156 patients, with 23 patients requiring surgical intervention over the 5-year period. Significant aortic stenosis (n = 43) and mitral regurgitation (n = 48) were the most common pathologies. Patients > 65 years were more likely to have structural heart disease (16% vs 11%, P < 0.05).
Conclusion:
Establishing a HMC has allowed the screening of a large number of patients who would otherwise have low priority for assessment. We have identified a large proportion with significant structural disease, which has allowed for early surgical intervention when appropriate and may potentially result in improved patient outcomes.
More Related Videos
11:50High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
Published on: July 9, 2010
04:48Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
Published on: November 28, 2018
Related Concept Videos
Cardiovascular System Abnormal Findings II: Auscultation
Abnormal Heart Sounds
Gallops:
Heart Sounds
Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V)...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests