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Updated: Mar 11, 2026

Facile Preparation and Photoactivation of Prodrug-Dye Nanoassemblies
Published on: February 17, 2023
Coordination-Induced Assembly of Intelligent Polysaccharide-Based Phototherapeutic Nanoparticles for Cancer Treatment
Ye Tian1, Ranran Guo1, Yajun Wang2
1State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai, 200433, P. R. China.
Abstract:
Smart polysaccharide-based anticancer phototherapeutic nanoparticles are prepared via a coordination-induced assembly process. Upon irradiated with a near infrared laser, the nanoparticles are not only able to simultaneously generate reactive oxygen species and hyperthermia that ablate tumors, but also possess tumor microenvironment-responsive off/on near infrared fluorescence and enhancement in photothermal effect, making them promising theranostic platform of cancer.

