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Biomarkers in Veterinary Medicine
Michael J Myers1, Emily R Smith1, Phillip G Turfle1
1Center for Veterinary Medicine, Food and Drug Administration, Rockville, Maryland 20855;
Annual Review of Animal Biosciences
|November 19, 2016
Summary
This review defines biomarkers, outlines their discovery and use, and provides examples in veterinary medicine and drug development. Collaboration between human and veterinary medicine can advance biomarker research.
Area of Science:
- Biomarker research
- Veterinary medicine
- Drug development
Background:
- Biomarkers are crucial for disease diagnosis, prognosis, and treatment monitoring.
- Standardized definitions and discovery processes are essential for reliable biomarker application.
- Current applications of biomarkers in veterinary medicine and drug development require further exploration.
Purpose of the Study:
- To define key terms associated with biomarkers.
- To review the general processes of biomarker discovery, validation, and implementation.
- To summarize and examine existing biomarker examples in veterinary clinical practice and drug development.
Main Methods:
- Literature review and synthesis of existing research.
- Analysis of definitions and processes in biomarker science.
- Compilation and categorization of biomarker examples from human and veterinary medicine.
Main Results:
- Established clear definitions for various biomarker types.
- Outlined a comprehensive workflow for biomarker discovery and validation.
- Identified diverse biomarker applications in animal health and pharmaceutical research.
Conclusions:
- Biomarker research holds significant potential for advancing veterinary diagnostics and therapeutics.
- Enhanced collaboration between human and veterinary medical research communities can accelerate progress.
- Leveraging resources and knowledge from human medicine is key to supporting biomarker discovery and validation in veterinary medicine.
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