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A Simple Thermoplastic Substrate Containing Hierarchical Silica Lamellae for High-Molecular-Weight DNA Extraction
Ye Zhang1, Yi Zhang1,2, Jeffrey M Burke3
1Biomedical Engineering Department, Johns Hopkins University, Baltimore, MD 21218, USA.
Advanced Materials (Deerfield Beach, Fla.)
|November 19, 2016
Abstract:
An inexpensive, magnetic thermoplastic nanomaterial is developed utilizing a hierarchical layering of micro- and nanoscale silica lamellae to create a high-surface-area and low-shear substrate capable of capturing vast amounts of ultrahigh-molecular-weight DNA. Extraction is performed via a simple 45 min process and is capable of achieving binding capacities up to 1 000 000 times greater than silica microparticles.
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