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A tonsillectomy increased the risk of chronic rhinosinusitis among children: A three-year follow-up study
Shiu-Dong Chung1, Herng-Ching Lin2, Chuan-Song Wu3
1Department of Surgery, Far Eastern Memorial Hospital, New Taipei City, Taiwan; Graduate Program in Biomedical Informatics, College of Informatics, Yuan-Ze University, Chung-Li, Taiwan; Sleep Research Center, Taipei Medical University, Taipei, Taiwan.
Objectives:
The study aimed to estimate the risk of developing chronic rhinosinusitis (CRS) among children who had undergone a tonsillectomy by utilizing a cohort study based on a population-based database.
Methods:
Data for this retrospective cohort study were sourced from the Taiwan "Longitudinal Health Insurance Database 2000". We included 202 children who had undergone a tonsillectomy as the study group and 2020 sex- and age-matched children as the comparison group. We used stratified Cox proportional hazard regressions to calculate the hazard ratio (HR) and its corresponding 95% confidence interval (CI) for CRS during the 3-year follow-up period.
Results:
Of 2222 sampled children, the incidence rate of CRS during the 3-year follow-up period was 3.2 (95% CI = 2.0-4.8) 1000 person-years; 18.2 (95% CI = 9.1-32.5) per 1000 person-years and 1.7 (95% CI = 0.8-3.0) per 1000 person-years for the study and comparison group, respectively. The stratified Cox proportional analysis showed that the adjusted hazard ratio for CRS during the 3-year follow-up period was 8.28 (95% CI = 3.24-21.16) for children who had undergone a tonsillectomy than comparison patients.
Conclusions:
We demonstrated that the risk of developing CRS is significantly increased among children who have undergone a tonsillectomy.
