[Von Willebrand factor in juvenile rheumatoid arthritis]

Forty-three patients with juvenile rheumatoid arthritis were examined. In children with active disease pattern, Willebrand's factor (WF) appeared on the average to be more than twice as increased comparatively to normal. The relationship was established between WF and the characteristics of the inflammatory process activity. The study of the platelet component of hemostasis made it possible to reveal activation of platelet aggregation despite the routine disaggregation and anti-inflammatory therapy, which requires constant laboratory control.