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Related Experiment Videos

Zinc: the neglected nutrient.

G E Shambaugh1

  • 1Shambaugh Hearing and Allergy, Hinsdale, IL 60521.

The American Journal of Otology
|March 1, 1989
PubMed
Summary
This summary is machine-generated.

Zinc deficiency impacts growth and fertility in animals and humans. Supplementing zinc can improve hearing loss and tinnitus in some elderly adults, suggesting it may cause presbycusis.

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Area of Science:

  • Human Nutrition
  • Otolaryngology
  • Trace Element Metabolism

Background:

  • Zinc's essential role in animal health was identified in 1916, linked to growth and reproduction.
  • Human zinc deficiency was first documented in Egyptian dwarfs, who showed developmental improvements with zinc supplementation.
  • Zinc is crucial for various bodily functions, with high concentrations found in the cochlea and vestibule.

Purpose of the Study:

  • To explore the link between zinc deficiency and hearing impairment, specifically presbycusis.
  • To investigate the potential of zinc supplementation in treating age-related hearing loss and tinnitus.

Main Methods:

  • Clinical diagnosis of zinc deficiency using serum zinc assays.
  • Observational study of elderly adults with marginal zinc deficiency and hearing issues.

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  • Administration of zinc supplementation to assess effects on tinnitus and sensorineural hearing loss.

    • Main Results:

    • Zinc deficiency is associated with developmental issues like dwarfism and sterility.
    • The cochlea and vestibule have higher zinc concentrations than previously assumed.
    • Approximately one-third of elderly patients with marginal zinc deficiency experienced improved tinnitus and sensorineural hearing loss after zinc supplementation.

    Conclusions:

    • Zinc deficiency is a potential contributing factor to presbycusis (age-related hearing loss).
    • Early recognition and correction of zinc deficiency may help arrest progressive hearing loss.
    • Further research is warranted to fully elucidate the role of zinc in auditory health.