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Updated: Mar 11, 2026
Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Are the AMPLATZER Duct Occluder II Additional Sizes devices dedicated only for smaller children?
Roland Fiszer1, Maciej Chojnicki, Małgorzata Szkutnik
1Department of Congenital Heart Diseases and Pediatric Cardiology, Medical University of Silesia, Zabrze, Poland.
Insights
The AMPLATZER Duct Occluder II Additional Sizes (ADOIIAS) effectively closes patent ductus arteriosus (PDA) in patients of all ages. This device offers a safe and successful alternative to coil implantation for PDA treatment.
Area of Science:
- Interventional Cardiology
- Pediatric Cardiology
- Medical Device Technology
Background:
- Patent ductus arteriosus (PDA) is a common congenital heart defect requiring closure.
- Various devices and techniques exist for PDA closure, each with specific indications and limitations.
- The AMPLATZER Duct Occluder II Additional Sizes (ADOIIAS) is a newer device designed for PDA closure.
Purpose of the Study:
- To evaluate the safety and efficacy of the ADOIIAS for closing different types of PDA.
- To assess the device's performance across a wide range of patient age groups.
- To present clinical experience with the ADOIIAS in a real-world setting.
Main Methods:
- Retrospective analysis of 103 patients who underwent PDA closure with ADOIIAS.
- Patients had PDA with a diameter below 3.5 mm.
- Ductal anatomy was classified using angiography (Types A, C, D, E).
Main Results:
- Successful PDA occlusion was confirmed in all patients post-procedure.
- The median patient age was 3.0 years, with 53.4% older than three years.
- Two cases of device embolization occurred, with successful percutaneous retrieval; one unrelated death was reported.
Conclusions:
- The ADOIIAS is a viable therapeutic option for selected PDA cases.
- The device demonstrated successful outcomes across all age groups.
- ADOIIAS can be a substitute for coil implantation in PDA closure.
Aims:
The aim of this study was to present our experience with the AMPLATZER Duct Occluder II Additional Sizes (ADOIIAS) for the closure of different types of patent ductus arteriosus (PDA) in patients of various age groups.
Methods And Results:
A group of 103 patients, in whom the PDA (diameter below 3.5 mm) was closed using the ADOIIAS, was analysed. The median age of treated patients was 3.0 years (from 0.1 to 24 years), and 55 patients (53.4%) were older than three years. Ductal anatomy defined by angiography showed type A in 42 patients (40.8%), type C in six patients (5.8%), type D in 21 patients (20.5%), and type E in 34 patients (33.0%). In two cases, embolisation of the device occurred shortly after implantation. Both occluders were retrieved percutaneously. One death occurred in a neonate four days after ADOIIAS implantation (not related to the procedure: multi-organ failure). Total occlusion of PDA was confirmed in all patients the day after the procedure. No protrusion of the device into the aorta or pulmonary artery was observed in any patient during follow-up.
Conclusions:
The use of the ADOIIAS is a good therapeutic option for the treatment of selected PDA. The implant may be successfully substituted for coil implantation in all age groups.
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