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Growth and prevalence of feeding difficulties in children with Robin sequence: a retrospective cohort study

Emma C Paes1, Iris A C de Vries2, Wouter M Penris3

  • 1Department of Pediatric Plastic Surgery, Wilhelmina Children's Hospital, University Medical Centre, PO Box 85500, 3508, GA, Utrecht, The Netherlands. emmapaes@gmail.com.

Clinical Oral Investigations
|November 22, 2016
PubMed

Insights

Infants with Robin sequence (RS) experience more feeding difficulties (FD) and lower growth rates compared to those with isolated cleft palate. Early recognition and treatment of FD are crucial for optimal development in RS patients.

Area of Science:

  • Craniofacial anomalies
  • Pediatric surgery
  • Developmental pediatrics

Background:

  • Robin sequence (RS) is associated with breathing problems and significant feeding difficulties (FD).
  • Limited data exists on the prevalence of FD and its influencing factors in RS patients.
  • Understanding these factors is essential for improving management strategies.

Purpose of the Study:

  • To determine the incidence of feeding difficulties (FD) in infants with Robin sequence (RS).
  • To identify factors influencing FD and growth in RS patients.
  • To compare FD and growth between RS and isolated cleft palate (iCPO) infants.

Main Methods:

  • A retrospective comparative cohort study included 69 RS infants and 64 iCPO infants.
  • Data on feeding, growth, and airway interventions were collected over the first two years of life.
  • A systematic literature review identified reported FD in RS patients.

Main Results:

  • RS infants exhibited higher rates of FD (91%) compared to iCPO infants (72%).
  • Nasogastric (NG)-tube feeding was required more frequently and for longer durations in RS patients.
  • RS infants showed significantly lower growth than iCPO infants, although growth was not affected by airway management or cleft palate grade.

Conclusions:

  • Feeding difficulties are prevalent in infants with Robin sequence, necessitating early detection and intervention.
  • Lower growth rates in RS patients highlight the need for vigilant monitoring and long-term follow-up.
  • Optimizing treatment strategies for FD is critical for ensuring adequate growth and development in RS patients.
Abstract

Keywords:
(Pierre) Robin sequenceCleft palateFeeding difficultiesGrowthSystematic reviewTreatmentWeight

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