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Exacerbation of bleeding with renal insufficiency
Indiana Medicine : the Journal of the Indiana State Medical Association
|June 1, 1989
Summary
Elderly patients with peptic ulcer bleeding and kidney issues may have bleeding problems due to renal disease. Cryoprecipitate effectively stopped bleeding by correcting this hemostatic defect.
Area of Science:
- Nephrology
- Hematology
- Gastroenterology
Background:
- Upper gastrointestinal bleeding is a common emergency, particularly in elderly patients.
- Peptic ulcer disease is a frequent cause of upper gastrointestinal bleeding.
- Renal insufficiency is prevalent in the elderly and can complicate bleeding management.
Observation:
- An elderly patient presented with upper gastrointestinal bleeding from a peptic ulcer.
- The bleeding was exacerbated by an underlying hemostatic defect linked to renal disease.
- This defect resulted in prolonged bleeding time.
Findings:
- Cryoprecipitate infusion was administered to address the hemostatic defect.
- Cryoprecipitate successfully reversed the hemostatic abnormality.
- Clinical bleeding was effectively controlled following cryoprecipitate administration.
Implications:
- Renal insufficiency in the elderly can cause or worsen hemostatic defects, complicating bleeding.
- Healthcare providers should consider associated hemostatic defects in elderly patients with renal disease and bleeding.
- Cryoprecipitate is a potential therapeutic option for managing bleeding associated with renal disease-related hemostatic defects.