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Updated: Feb 19, 2026
Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
Published on: January 12, 2022
Optical computing for optical coherence tomography
Xiao Zhang1, Tiancheng Huo1, Chengming Wang1
1State Key Laboratory of Low-dimensional Quantum Physics and Center for Atomic and Molecular Nanoscience, Department of Physics, Tsinghua University and Collaborative Innovation Center of Quantum Matter, Beijing 100084, China.
Abstract:
We propose an all-optical Fourier transformation system for real-time massive data processing in high speed optical coherence tomography (OCT). In the so-called optical computing OCT, fast Fourier transformation (FFT) of A-scan signal is optically processed in real time before being detected by photoelectric detector. Therefore, the processing time for interpolation and FFT in traditional Fourier domain OCT can be dramatically eliminated. A processing rate of 10 mega-A-scans/second was experimentally achieved, which is, to our knowledge, the highest speed for OCT imaging. Due to its fiber based all-optical configuration, this optical computing OCT system is ideal for ultrahigh speed volumetric OCT imaging in clinical application.
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