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Updated: Mar 11, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
[Gestational alloimmune liver disease: a case report]
Sara Laliena Aznar1, Inés Martínez Redondo2, María J Oliván Del Cacho2
1Hospital Infantil Miguel Servet, Zaragoza, España. saralaKena@gmail.com.
Abstract:
Gestational alloimmune liver disease, previously known as neonatal hemochromatosis, is characterized by severe liver disease in neonatal period, associated with intra and extrahepatic iron accumulation. It is postulated an alloimmune origin, which has opened new opportunities in the treatment and prevention during risk pregnancies, changing the prognosis of this pathology. We report the case of a newborn that presents early liver failure, with clinical and analytical features compatible with gestational alloimmune liver disease. Exchange transfusion was made and gamma globulins were given, with good clinical evolution.
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