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Vancomycin-resistant Enterococcus bacteremia in a child with acute myeloid leukemia: successful treatment with

Ayşe Büyükcam1, Eda Karadağ Öncel2, Yasemin Özsürekçi2

  • 1Pediatric Infectious Diseases Unit, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey. dr.aysebaktir@gmail.com.

Archivos Argentinos De Pediatria
|November 22, 2016
PubMed

Insights

Vancomycin-resistant enterococcus (VRE) infections pose a significant threat to children, especially those with leukemia. Daptomycin demonstrated success in treating a pediatric patient with VRE bacteremia, suggesting its potential as an alternative therapy.

Area of Science:

  • Pediatric Infectious Diseases
  • Hematology-Oncology
  • Antimicrobial Resistance

Background:

  • Multiple-drug-resistant enterococcal infections present a serious challenge in pediatric patients, often associated with severe underlying conditions.
  • Limited treatment options exist for pediatric patients with vancomycin-resistant enterococcus (VRE) infections compared to adults.

Observation:

  • A case report details a 3-year-old boy diagnosed with acute myeloid leukemia (AML)-M7.

Findings:

  • The patient experienced vancomycin-resistant enterococcus (VRE) bacteremia, a serious complication.
  • Successful treatment of VRE bacteremia was achieved using daptomycin.

Implications:

  • Daptomycin may represent a viable therapeutic option for VRE infections in pediatric populations.
  • Further research is warranted to establish the extended use and efficacy of daptomycin in treating pediatric VRE infections.

Keywords:
ChildDaptomycinLinezolidVancomycin resistant Enterococci

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