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Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells
Published on: November 18, 2016
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Stem cell bioprinting for applications in regenerative medicine
Brad J Tricomi1, Andrew D Dias2, David T Corr1
1Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, New York.
Annals of the New York Academy of Sciences
|November 22, 2016
Summary
Bioprinting precisely positions stem cells in complex scaffolds for regenerative medicine. This advanced technique enables intricate tissue engineering and vascular network creation, overcoming traditional limitations.
Area of Science:
- Regenerative Medicine
- Biotechnology
- Tissue Engineering
Background:
- Traditional tissue engineering struggles with complex structures and precise cell placement.
- Stem cells offer great potential but require controlled microenvironments.
- Bioprinting emerges as a solution for intricate scaffold and cell distribution needs.
Purpose of the Study:
- To review recent advancements in stem cell bioprinting.
- To explore bioprinting's utility in directing stem cell fate and engineering tissues.
- To discuss challenges in bioprinting living stem cells.
Main Methods:
- Programmed deposition of cells and biomaterials.
- Focus on recent literature and performance data in stem cell bioprinting.
- Analysis of applications in regenerative medicine.
Main Results:
- Bioprinting enables precise control over cell position and spatial distribution.
- Demonstrated capability in directing stem cell fate and engineering tissues.
- Successful creation of functional vascular networks using bioprinting.
Conclusions:
- Stem cell bioprinting is a powerful tool for regenerative medicine.
- It overcomes limitations of traditional methods in creating complex tissue constructs.
- Further research is needed to address stem cell viability and potency during bioprinting.
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