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Updated: Mar 11, 2026

Mesenchymal Stromal Cell Culture and Delivery in Autologous Conditions: A Smart Approach for Orthopedic Applications
Published on: December 8, 2016
Bone Marrow Aspirate Concentrate for Bone Healing in Foot and Ankle Surgery
Joshua S Harford1, Travis J Dekker1, Samuel B Adams1
1Department of Orthopaedic Surgery, Duke University Medical Center, Durham, NC 27710, USA.
Abstract:
Autologous bone marrow aspirate concentrate (BMAC) has become a popular orthobiologic to augment bone healing. The potential benefit comes from osteoprogenitor cells and growth factors that can lead to new bone formation in the setting of foot and ankle arthrodesis procedures. BMAC has an excellent safety record and has demonstrated efficacy in animal models of bone healing. Although scant, the literature on the use of BMAC in foot and ankle surgery does demonstrate promise for this orthobiologic adjuvant.

