Related Experiment Video
Updated: Mar 11, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Regional variation in acute stroke care organisation
Paula Muñoz Venturelli1, Thompson Robinson2, Pablo M Lavados3
1The George Institute for Global Health, University of Sydney, Sydney, Australia; Unidad de Neurología Vascular, Servicio de Neurología, Departamento de Medicina, Clínica Alemana de Santiago, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Santiago, Chile.
Hospitals in high-income countries (HIC) provided faster stroke care and more thrombolysis than middle-income country (MIC) hospitals. Differences in stroke care organization and treatment were observed, impacting patient outcomes.
Area of Science:
- Global Health
- Neurology
- Health Services Research
Background:
- Limited data exists on regional variations in stroke service organization, including healthcare resources, protocols, and discharge planning.
- This study compares stroke care organization in middle-income countries (MIC) and high-income countries (HIC) within the Head Position in Stroke Trial (HeadPoST).
Purpose of the Study:
- To compare the organization of stroke care between hospitals in middle-income countries (MIC) and high-income countries (HIC).
- To identify differences in healthcare resourcing, protocols, and discharge planning for stroke patients.
Main Methods:
- Utilized data from the Head Position in Stroke Trial (HeadPoST) international multicenter trial.
- A stroke care organization questionnaire was administered to participating hospitals.
- Hospitals were classified as MIC or HIC based on World Bank gross national income per capita criteria.
Main Results:
- 94 hospitals (51 MIC, 43 HIC) completed the questionnaire.
- HIC hospitals demonstrated significantly higher rates of patients arriving within 4 hours of symptom onset (41% vs. 13%) and receiving intravenous thrombolysis for acute ischemic stroke (10% vs. 5%).
- While most hospitals had dedicated stroke units and access to physicians, HIC hospitals offered greater access to a wider range of rehabilitation therapists compared to MIC hospitals.
Conclusions:
- All participating hospitals provided advanced stroke care, but significant organizational and treatment differences exist between MIC and HIC settings.
- Further multilevel analyses are planned to investigate the impact of specific organizational factors on patient outcomes.
Related Concept Videos
Acute Coronary Syndrome IV: Interprofessional Care
Aneurysm III: Interprofessional Care
Venous Thrombosis III: Interprofessional Care
Acute Kidney Injury V: Interprofessional Care

