Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tramadol Abuse and Sexual Function.

Ibrahim A Abdel-Hamid1, Karl-Erik Andersson2, Marcel D Waldinger3

  • 1Division of Andrology, Mansoura Faculty of Medicine, Mansoura, Egypt.

Sexual Medicine Reviews
|November 23, 2016
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Biology and Time Course of Obstruction-Induced Detrusor Underactivity Causing Postvoid Residual Urine.

International neurourology journal·2026
Same author

Bladder under stress: Pathological and adaptive shifts in channel expression.

Channels (Austin, Tex.)·2026
Same author

Erectile and Clitoral Dysfunction as Harbingers of Cardiovascular Disease: A Perspective.

Medicina (Kaunas, Lithuania)·2026
Same author

Endogenous vasopressin and vasopressin receptor 2 in bladder as anti-diuretic / anti-spasmodic targets for the treatment of multifactorial nocturia.

Continence (Amsterdam, Netherlands)·2026
Same author

Urethral pharmacological mechanisms incontinence and bladder emptying: An updated review.

Bladder (San Francisco, Calif.)·2024
Same author

Cellular regenerative therapy in stress urinary incontinence: new frontiers?-a narrative review.

Translational andrology and urology·2024

Tramadol may help premature ejaculation (PE), but its abuse is a growing concern. More research is needed to understand tramadol

Area of Science:

  • Pharmacology and Toxicology
  • Sexual Medicine
  • Drug Abuse Research

Background:

  • Tramadol, an opioid agonist, is associated with abuse issues globally.
  • The impact of tramadol on sexual function is debated, with potential benefits for premature ejaculation (PE).
  • Patients using tramadol for PE are sensitive to developing other sexual dysfunctions.

Purpose of the Study:

  • To conduct a literature review on tramadol abuse.
  • To investigate the relationship between tramadol use and sexual function.
  • To define the benefits and risks of tramadol on ejaculation, orgasm, erection, desire, and testosterone levels.

Main Methods:

  • Systematic literature search of electronic databases (PubMed MEDLINE, EMBASE, etc.) from 1977 to September 2015.
Keywords:
EjaculationErectionHypogonadismSexual FunctionTramadol

Related Experiment Videos

  • Keywords used: tramadol, sexual functions, and sexual dysfunction.
  • Inclusion of data from clinical trials, systematic reviews, and meta-analyses.

    • Main Results:

    • Tramadol abuse is a significant problem in several countries, particularly in the Middle East, Africa, and West Asia.
    • Evidence from 11 clinical trials suggests tramadol may benefit PE.
    • Limited evidence exists regarding tramadol's impact on erectile dysfunction, libido, hypogonadism, anorgasmia, and risky sexual behaviors in abuse cases.

    Conclusions:

    • Tramadol could be a viable treatment for PE, but further rigorous trials are necessary.
    • The potential long-term risks and optimal dosage of tramadol require further investigation.
    • Research into drug abuse and sexual dysfunction is an emerging field needing more studies.